postpartum depression
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Those who intend to perform caesarean section under spinal anesthesia; 2) clearly understand and voluntarily participate in the study, and sign the informed consent form themselves.
Exclusion criteria
Exclusion criteria: 1) People with communication disorders; 2) People with high blood pressure during pregnancy or with severe cardiovascular diseases; 3) People with a history of hyperthyroidism; 4) People with a history of drug use; 5) People who are allergic to esketamine or with elevated intracranial pressure, elevated intraocular pressure and elevated intragastric pressure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postpartum depression six weeks after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Edinburgh Postpartum Depression scale score at 1 week, 2 weeks, 4 weeks and 6 weeks after operation;1, 2, 3 days of postoperative exercise and resting pain VAS score;Ramsay score of 5 minutes after drug injection, at the end of the operation, and 1 day after surgery;BPRS+ score of 5 minutes after drug injection, at the end of the operation, and 1 day after surgery;Postoperative Social Support Evaluation Scale Score at 6 Weeks;The times of PCA pressing, the total amount of drugs used and the use of remedial drugs;Vital signs (including heart rate, pulse oxygen and blood pressure) at 1min, 5min and 10min after drug injection and at the end of operation; | — |
Countries
China
Contacts
Public ContactWei Ke
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed