diarrheal Irritable Bowel Syndrome
Conditions
Interventions
Test group:complex-probiotic-preparation, take 4 capsules once a day for 4 weeks.
Control group:Placebo capsule, take 4 capsules once a day for 4 weeks.
Sponsors
Army Medical Center(Daping Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: ?Male or female, age 18-70 years old. ?The patient was diagnosed with diarrheal Irritable Bowel Syndrome(according to Roman criteria V), and the frequency of defecation was greater than 3 times/day, and the course of the disease was greater than 6 months. ? No mental illness, with normal communication ability. ? Sign informed consent and agree to participate in this study.
Exclusion criteria
Exclusion criteria: ? Complicated with other serious diseases, such as respiratory failure, heart failure and severe immune deficiency, with surgical indications or previous colon surgery. ? Combined with other diseases that affect the intestinal microbiota, such as metabolic syndrome and autoimmune diseases. ? Women in pregnancy, pregnancy and lactation. ? Use of antibiotics or probiotics within 1 week before enrollment. ? A history of severe allergies. ? Other clinical researchers in the process of enrollment or within 4 weeks before enrollment. ? Patients with poor compliance and difficulty in completing follow-up. ? Other reasons that the investigator thinks are not suitable for enrollment or subjects withdraw from the trial due to their own reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IBS symptom severity scale,IBS-SSS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gastrointestinal Symptoms Rating Scales,GSRS;Bristol stool form scale,BSS;face rating scale,FRS;intestinal flora;IBS symptom severity scale,IBS-SSS; | — |
Countries
China
Contacts
Public ContactYanling Wei
Army Medical Center(Daping Hospital)
Outcome results
None listed