Chronic obstructive pulmonary disease and cardiovascular disease
Conditions
Interventions
Intervention group 1:8 weeks of 50% to 60% MIP inspiratory muscle training, aerobic training, and resistance training.
Intervention group 2:8 weeks of 50% to 60% MIP inspiratory muscle training
Control group:Daily medical consultation
Sponsors
West China School of Public Health and West China Fourth Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) According to the American Thoracic Association (ATS)/Respiratory ERS standards, patients with FEV1/FVC<0.70 and diagnosed with mild or above chronic obstructive pulmonary disease (predicted forced expiratory volume in 1 second (FEV1) less than 80%); (2) Age over 40 years old; (3) Arterial wave conduction velocity: PWV = 1400mm/s; (4) Agree to participate in this experiment and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Has undergone pulmonary resection or lobectomy within the past 6 months; (2) Having pneumothorax or rib fractures; (3) Severe movement disorders (not caused by chronic obstructive pulmonary disease), or other neurological, muscular, skeletal, or cardiovascular diseases that seriously affect the safety of the subject's training; (4) Severe heart disease (acute heart failure or myocardial infarction, unstable angina, uncontrolled arrhythmia, third degree atrioventricular block patients, unexplained chest pain and palpitations); (5) Pregnancy or breastfeeding; (6) Individuals with cognitive impairment or other inability to cooperate with training; (7) Individuals who have not signed informed consent forms. (8) Participate in other similar experiments. (9) Strict inclusion and exclusion criteria will be applied to exclude subjects with a pulmonary bulla diameter greater than 1cm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary function;degree of arteriosclerosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| life-style;blood pressure;blood fat;blood sugar; | — |
Countries
China
Contacts
Public ContactShujuan Yang
West China School of Public Health and West China Fourth Hospital
Outcome results
None listed