Diaphragm weakness after laparoscopic cholecystectomy
Conditions
Interventions
deep neuromuscular block:Maintain a PTC count of 1-2 and a TOF count of 0
moderate neuromuscular block:Maintain a TOF count of 1-2
Sponsors
The First Affiliated Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients aged > 18 years, ASA grade I-III,elective laparoscopic cholecystectomy under general anesthesia.
Exclusion criteria
Exclusion criteria: 1.Emergency surgery or unexpected hemorrhagic shock during surgery; 2.Allergy to any of the drugs used in anesthesia; 3.History of severe heart, lung, liver, kidney, neurological, hematological disease or neuromuscular disorders and diaphragmatic paralysis; 4.Treatment with drugs known to affect neuromuscular function or cause drowsiness within 2 weeks before surgery; 5.Psychiatric and skin conditions that may interfere with the study protocol or potentially confound results; 6.Patients who had participated in another study within 6 month; 7.Pregnancy or breastfeeding; 8.Patients refused to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragm thickening fraction during tidal breathing; | — |
Secondary
| Measure | Time frame |
|---|---|
| Diaphragm thickness during tidal breathing;Diaphragm excursion during tidal breathing;Incidence of diaphragm weakness;Postoperative pain score;Diaphragm thickening fraction during maximal inspiration;Diaphragm thickeness during maximal inspiration;Diaphragm excursion during maximal inspiration;Diaphragm thickness during tidal breathing;Incidence of postoperative hypoxemia; | — |
Countries
China
Contacts
Public ContactJiehao Sun
The First Affiliated Hospital, Wenzhou Medical University
Outcome results
None listed