Postoperative delirium
Conditions
Interventions
Part 1 Study:Cerebral oxygen saturation monitoring blind group:Anesthesiologists are unable to view real-time cerebral oxygen monitoring data during surgery (cerebral oxygen saturation monitoring is p
Part 1 Study:Cerebral oxygen saturation monitoring intervention group:Anesthesiologists can view the cerebral oxygen monitoring data in real time during the operation, and maintain the intraoperative
The second part studies:Cerebral oxygen saturation group:Anesthesiologists can view brain oxygen monitoring data in real time during surgery, and interfere with rSO2 values when they fluctuate by more
The second part studies:Brain oxygen saturation true variability group:Anesthesiologists can view brain oxygen monitoring data in real time during surgery and interfere with the true variation rate of
Sponsors
The Second Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: 1. Age 60-80 years; 2. Patients with mild anemia [preoperative hemoglobin (Hb) 90g/L= < 120g/L, 90g/L for males =110g/L for females< 110g/L]; 3. ASA Class II~III; 4. Patients undergoing hip arthroplasty; 5. Patients and their families sign an informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: 1. Patients with non-anemia and moderate to severe anemia [preoperative hemoglobin Hb: male=120g/L, female=110g/L are not anemic; 60~90g/L is moderate, 30~60g/L is severe]; 2. History of severe cerebrovascular accident; 3. History of long-term use of psychotropic drugs within six months before admission, and long-term alcoholism; 4. Severe visual, auditory or verbal communication impairment; 5. Severe renal dysfunction; 6. Refusal to use postoperative analgesia in patients; 7. The Mini-Mental State Scale (MMSE) score performed before surgery cannot be matched with the score measurement and is lower than the minimum score of the corresponding education level (illiteracy> 17 points, 20 points for primary school >, and 24 points > junior high school and above. )
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The first part studies intraoperative low rSO2 events;Preoperative cognitive function score;Baseline value of preoperative cerebral oxygen;Postoperative delirium evaluation;The second part studies intraoperative low rSO2 events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative hemoglobin value and other abnormal indicators, postoperative blood gas analysis value, hemoglobin value and other abnormal indicators rechecked within three days after surgery.;Intraoperative anesthetic drug dosage, vasoactive drug type and dosage, infusion volume, and blood loss;Duration of surgery, duration of anesthesia, length of stay in PACU, length of hospital stay, VAS score at 1, 2, 3 d postoperatively, and postoperative complications; | — |
Countries
China
Contacts
Public ContactHu Xianwen
The Second Hospital of Anhui Medical University
Outcome results
None listed