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Clinical application of BKV-antigen-specific T lymphocyte for monitoring BKV infection

Clinical application of BKV-antigen-specific T lymphocyte for monitoring BKV infection

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400085443
Enrollment
Unknown
Registered
2024-06-07
Start date
2024-06-07
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

kidney transplantation

Interventions

Kidney Transplantation Recipients group:None

Sponsors

The First Affiliated Hospital of Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) older than 18 years and younger than 65 years; (2) first renal transplantation; (3) same or compatible ABO blood group between donor and recipient; (4) patients who signed informed consent and were willing to cooperate with the study.

Exclusion criteria

Exclusion criteria: (1) pregnant or lactating female patients; (2) the patient has any form of drug abuse, mental illness or any situation that researchers believe may interfere with the patient's understanding of research requirements; (3) those who do not meet the selection criteria; (4) contraindication of immunosuppressant and hormone use; (5) active peptic ulcer; (6) patients with severe heart and lung diseases; (7) patients with active liver disease; (8) patients with previous malignant tumors (except locally treated non-melanocytic skin cancer) ; (9) patients who could not be followed up with a routine study visit or follow-up, or who were followed up in an unaccredited laboratory. (10) Liver-kidney, pancreas-kidney or heart-kidney transplantation recipients.

Design outcomes

Primary

MeasureTime frame
BKV-ELISPOT;

Secondary

MeasureTime frame
Blood polyoma virus DNA detection;Blood concentration of immunosuppressants was monitored;Biochemical indexes of renal function;urinalysis;

Countries

China

Contacts

Public ContactXiaoming Ding

The First Affiliated Hospital of Xi'an Jiaotong University

xmding1970@126.vpm+86 139 9123 8632

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026