Compared the clinical outcomes of natural cycle and hormone replacement cycle for endometrial preparation in frozen embryo transfer: a prospective randomized controlled trial of single center

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400085422

Enrollment

Unknown

Registered

2024-06-06

Start date

2022-12-01

Completion date

Unknown

Last updated

2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Experimental group:estradiol valerate

Control group:no

Eligibility

Sex/Gender

Female

Age

20 Years to 42 Years

Inclusion criteria

Inclusion criteria: 1. Age <= 42 years old; 2. Regular menstrual cycle (25-35 days); 3. The first or second frozen embryo transfer cycle; 4. Sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Endometriosis; 2. Recurrent abortion; 3. Uterine malformation; 4. Hydrosalpinx without surgical treatment; 5. Intrauterine adhesions or thin endometrium, endometrial polyps, or other uterine factors.

Design outcomes

Primary

Measure	Time frame
Live birth rate;	—

Secondary

Measure	Time frame
Clinical pregnancy rate;Spontaneous miscarriage rate;Maternal and infant complications;Embryo implantation rate;	—

Countries

China

Contacts

Public ContactWeijie Xing

The Third Affiliated Hospital of Sun Yat-sen University

838295988@qq.com+86 158 1338 6589

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026