Heart failure
Conditions
Interventions
Sponsors
Fu Xing Hospital,Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) age 18 years or older 2) symptomatic heart failure, NYHA Class II-IV 3) receiving at least 3 months of optimal treatment for heart failure 4) hemoglobin HGT>80 G/L 5) glomerular filtration rate =30 ml/min 6) alanine aminotransferase A LT>150 U/L 7) signed informed consent and were able to complete follow-up
Exclusion criteria
Exclusion criteria: 385/2000 1) patients treated with antibiotics or probiotics within 4 weeks 2) multiple drug combinations with an increased risk of interaction 3) patients with malignancy 4) impaired liver function alanine aminotransferase =150 U L 5) persistent infections including gastrointestinal infections 6) inflammatory bowel disease 7) intestinal obstruction 8) active myocarditis 9) severe primary valvular heart disease 10) cardiac resynchronization therapy initiated within 6 months 11) other severe comorbidities 12) continuous immunosuppressive drug therapy 13-RRB- continuous rifamycin therapy 14) Central venous catheter implantation 15) pregnancy or planned pregnancy 16) poor adherence
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma Tmao;Fecal flora;Cardiovascular death or rehospitalization; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of hospital stay; | — |
Countries
CHina
Contacts
Public ContactYe Jia
Fu Xing Hospital,Capital Medical University
Outcome results
None listed