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Effect of propofol combined with remimazolam besylate on blood pressure after general anesthesia induction

Effect of propofol combined with remimazolam besylate on blood pressure after general anesthesia induction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085401
Enrollment
Unknown
Registered
2024-06-06
Start date
2023-04-12
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-induction hypotension

Interventions

Propofol group:Intravenous bolus of propofol 2.0 mg/kg, sufentanil 0.4 micrograms/kg, and rocuronium bromide 0.8 mg/kg
Propofol combined with remimazolam besylate group:Intravenous bolus of remimazolam besylate 0.2 mg/kg, propofol 1.0 mg/kg, sufentanil 0.4 µg/kg, and rocuronium bromide 0.8 mg/kg were administered
Remimazolam besylate group:Intravenous remimazolam besylate 0.4 mg/kg, sufentanil 0.4 micrograms/kg, and rocuronium bromide 0.8 mg/kg

Sponsors

Yancheng Maternal and Child Health Care Hospital Affiliated to Yangzhou University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
19 Years to 65 Years

Inclusion criteria

Inclusion criteria: Gynecologic laparoscopic surgery patients under elective general anesthesia endotracheal intubation, ASA grade I or II, age 19~65 years old

Exclusion criteria

Exclusion criteria: Participated in other clinical trials at the same time, refused to participate in this trial, body mass index (BMI) >35, surgery for normal pregnant women, allergy to lipid emulsion or remimazolam besylate

Design outcomes

Primary

MeasureTime frame
Blood pressure;

Secondary

MeasureTime frame
Heart rate;Bispectral index;Mortality within 30 days;

Countries

China

Contacts

Public ContactZhao Xinmin

Yancheng Maternal and Child Health Care Hospital Affiliated to Yangzhou University

zxmfby@163.com+86 152 9531 7979

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026