metabolic associated fatty liver disease
Conditions
Interventions
Gold Standard:According to the pathological staging results of the gold standard liver biopsy, the non-case group was defined as having no liver fibrosis (S0 stage), while the case group was defined a
Index test:2D-SWE GE Ultrasound Diagnostic Instrument
a. Before the examination, the patient should fast for 2-3 hours and rest for 10 to 20 minutes.
b. Instrument settings: The elastography sampling
Sponsors
The First Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Patients suspected of having non-alcoholic fatty liver disease (NAFLD) (suggested by any imagingexamination) who voluntarily sian the informed consent form, 2.Undergo both two-dimensional shear wave elastography and transient elastography on the same day, 3.Undergo ultrasound-guided liver biopsy in our department; 4.Be at least 18 years old.
Exclusion criteria
Exclusion criteria: A history of alcohol consumption for more than 5 years, with male patients consuming =40g of alcohol per day and female patients =20g per day, or excessive alcohol consumption in the past two weeks, with male patients consuming =80g of alcohol per day and female patients =40g per day; Viral hepatitis, drug-induced liver injury, autoimmune hepatitis, or other diseases that cause secondary hepatic steatosis; Patients with contraindications for liver biopsy; Decompensated liver disease (defined as a Child-Pugh score > 7); Patients who have undergone liver transplantation or TIPS surgery; Patients with malignant liver lesions; Pregnant women or women who wish to become pregnant; Any other factors deemed by the researchers as unsuitable for inclusion or that may affect participation or completion of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver stiffness measurement, LSM;Accuracy ;Sensitivity ;Specificity ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive predicative value;Negative predictive value; | — |
Countries
China
Contacts
Public ContactDezhi Zhang
The First Hospital of Jilin University
Outcome results
None listed