dry skin
Conditions
Interventions
Treatment Group:Inject crosslinked chittin gel
Control Group:no treatment
Sponsors
Guangdong Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Age 18-60 years old (including both ends), male and female; 2) Patients with dry skin, dark skin tone and mild to severe fine lines (score of 1 to 3 on the Skin fine Lines Scale) who were judged by the injection investigator and wanted to improve; 3) The skin Fitzpatrick type was ?-?; 4) Willingness to maintain existing skin care habits during the study period; 5) Voluntarily participate in the study, sign informed consent, fully understand the test content, process and possible adverse reactions, and agree to participate in all visits, examinations and treatments as required by the test plan.
Exclusion criteria
Exclusion criteria: 1) Pregnant, nursing and puerperal women and those who have a pregnancy plan within the last 1 year; 2) There are serious mental disorders, psychological disorders, personality disorders or are taking antipsychotic drugs; 3) have a history of serious diseases of important organs (cardiovascular system, lung, liver, kidney and nervous system, etc.); 4) diabetes, autoimmune disease or abnormal coagulation function; 5) Have received thrombolysis, anticoagulation, antiplatelet aggregation therapy within 2 weeks before injection, or need to receive the above treatment within 2 weeks after injection; 6) There are systemic and treatment site infections; 7) Allergic, inflammatory skin diseases (such as acute onset dermatitis, eczema, acne, seborrheic dermatitis, rosacea), unhealed wounds, infections, precancerous lesions or cancerous changes on the face; 8) cicatricial constitution (easy to form hypertrophic scars or keloids); 9) People who are allergic to polysaccharide substances such as chitin or any component of this product, allergic to local anesthetic drugs (such as lidocaine or other amide narcotic drugs), or have a history of severe allergy or multiple allergies; 10) Those who have the following prior treatment or plan to undergo the following treatment during the study period: ? facial fat fillings or permanent implants, such as polymethyl methacrylate, silicone, polytetrafluoroethylene; ? Semi-permanent facial fillers such as calcium hydroxyapatite and poly-L-lactic acid were used within 36 months prior to enrollment. ? Temporary facial fillers, such as sodium hyaluronate and collagen, within 12 months before enrollment; ? Within 6 months before enrollment, patients had received facial injection of botulinum toxin, facial plastic surgery, or comprehensive photoelectric therapy or beautic-plastic therapy; ? Change skin care habits (including topical products, oral products or sun protection habits) within 30 days prior to enrollment; 11) Long-term outdoor work or postoperative need for a lot of exposure to sunlight; 12) Participants in any other clinical trial within 30 days before signing the informed consent; 13) There are circumstances that other investigators judge are not suitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| GAIS; | — |
Secondary
| Measure | Time frame |
|---|---|
| improvement of skin roughness; | — |
Countries
China
Contacts
Public ContactLuo Shengkang
Guangdong Second People's Hospital
Outcome results
None listed