STROKE
Conditions
Interventions
Test group:Basic treatment: refer to the AHA/ASA 2019 Guidelines for the Treatment of Acute Stroke
In addition to the basic treatment, acupuncture treatment will be given by adding and subtracting acu
control group:Basic treatment: refer to the AHA/ASA 2019 Guidelines for the Treatment of Acute Stroke
Referring to previous high-quality studies related to acupuncture for constipation, the control gr
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
20 Years to 85 Years
Inclusion criteria
Inclusion criteria: ? All patients met the diagnostic criteria for stroke in the AHA/ASA 2019 Guidelines for the Treatment of Acute Stroke and the Clinical Practice Guidelines for Chinese Medicine Rehabilitation. ? They met the diagnostic criteria for functional constipation; ?Recovery period (2 weeks < duration of disease < 6 months) with stable vital signs; ?Basically normal cognitive comprehension and can cooperate to complete the study; ? not participating in other clinical trials; Patients were informed about the study and voluntarily signed the informed consent form.
Exclusion criteria
Exclusion criteria: ?Those with previous chronic constipation, cognitive dysfunction, mental disorders, and communication disorders; ?Those with a combination of other brain diseases, neurological diseases, and cardiopulmonary and other important organ insufficiencies; ? those with severe tumors, cardiovascular diseases (very high risk hypertension, coronary heart disease, pulmonary heart disease, etc.), autoimmune diseases (systemic lupus erythematosus, rheumatoid arthritis, ankylosing spondylitis, etc.) and hematologic diseases (coagulation disorders, hemophilia, purpura, aplastic anemia, etc.), respiratory failure or co-infections; ? those with constipation caused by the presence of organic lesions such as obstruction or polyps in the gastrointestinal tract, or those with a past history of severe chronic constipation; ? long-term use of drugs with side effects of constipation, such as anticholinergic drugs, antidepressants, etc.; or drugs being taken that affect vagal function (e.g., anticholinergics, antiarrhythmics, alpha or beta blockers, antibiotics) ?History of medical conditions associated with autonomic dysfunction (e.g., peripheral neuropathy, vagotomy, abnormal thyroid function, amyloidosis, asthma, heart failure, renal insufficiency, alcoholism); ? Other conditions that the investigator considers inappropriate for participation in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| oxytocin;Heart Rate Variability (HRV);LRP6;SBMs;CSBMs;PAC-SYM;PAC-QOL; | — |
Secondary
| Measure | Time frame |
|---|---|
| DAO;D-LA;LPS;NIH Stroke Scale;Barthel Scale;SAS; | — |
Countries
CHINA
Contacts
Public Contactlei chen
West China Hospital of Sichuan University
Outcome results
None listed