Clinical study of Chinese-Western collaborative rehabilitation program in post-stroke depression patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400085310

Enrollment

Unknown

Registered

2024-06-05

Start date

2024-06-05

Completion date

Unknown

Last updated

2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post stroke depression

Interventions

Chinese Western Collaborative Rehabilitation Team:On the basis of routine rehabilitation treatment, receive Shuguang characteristic traditional Chinese medicine collaborative treatment. (Tuina+acupunc

control group:Conventional rehabilitation therapy (cognitive-behavioral therapy). Once per day, 5 days per week, lasting for a total of 4 weeks

Eligibility

Sex/Gender

All

Age

45 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? The diagnosis meets the diagnostic standards of traditional Chinese medicine and Western medicine. ? Age range from 45 to 80 years old, regardless of gender. ? The patient voluntarily signs the informed consent form (if the patient is unable to sign the informed consent form due to physical disabilities or other reasons, the patient's family member shall sign on their behalf). ? Mild to moderate depression patients with a Hamilton Depression Rating Scale (HAMD-17) score greater than 7 but less than or equal to 24. ? Unconscious disorders, aphasia, heart function greater than or equal to level 3, stable vital signs.

Exclusion criteria

Exclusion criteria: ? Individuals with comorbid dementia (MMSE = 20), aphasia, cognitive impairment, and inability to cooperate in completing relevant tests such as the scale. ? Previous history of mental illness or family history of mental illness. ? Serious suicidal tendencies. ? Patients with unstable vital signs during the acute phase (within two weeks) or progression of stroke. ? Individuals with severe skin diseases or localized skin damage. ? There are contraindications for transcranial magnetic stimulation and magnetic resonance imaging (MRI) examination, such as the presence of pacemakers and metal implants in the body.

Design outcomes

Primary

Measure	Time frame
Hamilton Depression Scale;	—

Secondary

Measure	Time frame
mini-mental state examination;Borg Fatigue Rating Scale;Near infrared brain functional imaging;Functional magnetic resonance imaging;IL-6;IL-4;IL-10;IL-17;TNF-a;Interferon ?;Adrenocorticotropic Hormone(ACTH);cortisol;IL-1ß;	—

Countries

China

Contacts

Public ContactTao Jiming

Shuguang Hospital, Shanghai University of Traditional Chinese Medicine

taoyecheng@163.com+86 133 8619 2862

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026