depression
Conditions
Interventions
rTMS combined BCI training group:rTMS combined BCI pedaling training
sham rTMS combined BCI training group:sham rTMS combined BCI pedaling training
Sponsors
Department of rebabilitation medicine of Air Force Medical Center
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: (1) 18-55 years old, Han Chines with injury but not influence lower limb motor function; (2) Accord with the diagnostic criteria of unipolar, no-psychotic major depressive disorder (MDD) according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, text revision (DSM-IV-TR); (3) A sum of score of the 17-item Hamilton Depression Rating Scale (HDRS-17) was = 17. (4) Patients without sever orthopedic issue; (5) Without participated in aerobic training or any other exercise programs in the past 3 month;
Exclusion criteria
Exclusion criteria: (1) History of serious substance abuse, alcohol dependence or smoking. (2) History of musculoskeletal dysfunction, mental or neurological disorders; (3) A current head trauma or history of organic brain disorders; (4) Severe tenden-cy of suicide as shown by a score of 3 or 4 on the suicide item of HDRS-17; (5) Previous or current psychotropic treatment and psychotherapy; (6) Implanted device or metal in the brain or heart; (7) Previous or current receive other neurostimulation (including tDCS, iTBS and tACS);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cognitive function;neurotrophic performance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale-17 items;the Patient Health Questionnaire-9 items;the Generalized Anxiety Disorder scale-7 items;the Pittsburgh Sleep Quality Index; | — |
Countries
China
Contacts
Public ContactYe Chaoqun
Air Force Medical Center of Chinese PLA
Outcome results
None listed