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Effect of different antiemetic regimen on postoperative nausea and vomiting in gynecological general anesthesia patients

Effect of different antiemetic regimen on postoperative nausea and vomiting in gynecological general anesthesia patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085300
Enrollment
Unknown
Registered
2024-06-04
Start date
2024-06-05
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative nausea and vomiting

Interventions

Group A (control group):5mg dexamethasone was injected intravenously during anesthesia induction
Group B (intravenous granisetron group):5mg dexamethasone intravenously during induction of anesthesia and 2mg granisetron intravenously at the end of surgery
Group C (point injection with granisetron group):5mg dexamethasone was injected intravenically during anesthesia induction, and 2mg granisetron was injected into Neiguan point at the end of surgery
Group D (point injection with 0.9% normal saline group):5mg dexamethasone was injected intravenically during anesthesia induction, and 2ml 0.9% normal saline was injected into Neiguan point at the end
Group E (acupressure group):5mg dexamethasone was injected intravenically during anesthesia induction. At the end of the operation, the patient was given acupressure at Neiguan point with an elastic w

Sponsors

West China Second Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Women; Age range from 18 to 50 years old; ASAI-II level; Laparoscopic surgery; Unconscious and language communication barriers

Exclusion criteria

Exclusion criteria: Patients who refuse to participate in the study; Severe cardiorespiratory, hepatic, renal, neurological or endocrinal disease; Diabetes; Obesity; Allergies to Granisetron and Dexamethasone drugs; Patients who had taken H2 antagonists, antiemetic or psychoactive medication, nausea, retching or vomiting within 48 hours before surgery; Pregnant women; Lactating women

Design outcomes

Primary

MeasureTime frame
ausea level;Vomiting episode;

Countries

China

Contacts

Public ContactTian Wanli

Department of Anesthesiology Nursing, West China Second University Hospital

729912769@qq.com+86 136 6619 2271

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026