Helicobacter pylori treatment
Conditions
Interventions
test group:Tegolasen 50 mg 2/day
Colloidal bismuth pectin 200 mg 2/day
Cefuroxime axetil 500 mg 2/day
Clarithromycin 500 mg 2/day
Control group:Rabeprazole 10 mg 2 times a day
Colloidal bismuth pectin 200 mg 2/day
Cefuroxime axetil 500 mg 2/day
Clarithromycin 500 mg 2/day
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Age = 18 years old and = 70 years old, both men and women are welcome; 2) Clinical diagnosis of Helicobacter pylori infection (breath test and/or stool Hp test and/or pathological confirmation of HP positivity); 3) Penicillin allergy, or penicillin skin test positive; 4) Voluntary signing of the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Use of antibiotics, PPIs, P-CABs, bismuth or non-steroidal anti-inflammatory drugs within one month; 2) Pregnancy or lactation; 3) Allergy to the drugs used in the study; 4) Taking drugs that are incompatible with the test drugs; 5) Combination with serious underlying diseases or other diseases that may lead to ineffective treatment; 6) History of gastrointestinal surgery or recent history of other types of surgery; 7) Family history of genetic diseases, history of mental illness, etc.; 8) The research subject is participating in other research projects; 9) The researchers believe that it is not suitable to continue the clinical trial for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Helicobacter pylori eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of drug-related adverse reactions; | — |
Countries
China
Contacts
Public ContactShu Qing
Shenzhen Second People's Hospital
Outcome results
None listed