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The efficacy and safety of propofol combined with dexmedetomidine in the treatment of chronic insomnia: a prospective study

The efficacy and safety of propofol combined with dexmedetomidine in the treatment of chronic insomnia: a prospective study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085256
Enrollment
Unknown
Registered
2024-06-04
Start date
2024-06-10
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic insomnia

Interventions

After anesthesia treatment (experimental group):Application of propofol combined with dexmedetomidine combined with stellate ganglion block and insomnia cognitive therapy in the treatment of chronic i

Sponsors

Shihezi People's Hospital (Third Affiliated Hospital of Shihezi University School of Medicine)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: ? Meets the diagnostic criteria for chronic insomnia in the 2017 edition of the Chinese Adult Insomnia Diagnosis and Treatment Guidelines Before admission, patients received routine treatment in accordance with the 2017 edition of the Chinese Guidelines for the Diagnosis and Treatment of Adult Insomnia. There were more than two types of treatment drugs, and the treatment time exceeded 3 months. The treatment effect was poor or ineffective; Pittsburgh Sleep Quality Index (PSQI) score>9 before admission, diagnosed as chronic primary insomnia The patient voluntarily accepts this treatment and signs a written informed consent form, regardless of gender, aged between 18-70 years old.

Exclusion criteria

Exclusion criteria: Patients with sleep apnea syndrome, history of epilepsy, known alcoholism or drug dependence, pregnant or breastfeeding.

Design outcomes

Primary

MeasureTime frame
After treatment, the effective rate of treatment on the second day;End of treatment, effective treatment rate after 1 month;End of treatment, effective treatment rate after 3 months;After treatment, the improvement value of the Pittsburgh Sleep Quality Index score on the second day compared to before treatment;Improvement in Pittsburgh Sleep Quality Index (PSQI) score one month after treatment compared to before treatment;Improvement in Pittsburgh Sleep Quality Index (PSQI) score at 3 months after treatment compared to before treatment;

Secondary

MeasureTime frame
End of treatment, effective treatment rate after 6 months;Improvement in Pittsburgh Sleep Quality Index (PSQI) score 6 months after treatment compared to before treatment;

Countries

china

Contacts

Public Contactwuxiuling

Anesthesiology Department of Shihezi People's Hospital (Third Affiliated Hospital of Shihezi University School of Medicine) in Xinjiang

751564366@qq.com+86 182 9907 2057

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 20, 2026