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Effect of external diaphragmatic pacing on ventilator induced diaphragmatic dysfunction

Effect of extracorporeal diaphragmatic pacing on ventilator induced diaphragmatic dysfunction

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085238
Enrollment
Unknown
Registered
2024-06-03
Start date
2024-06-03
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator Induced Diaphragmatic Dysfunction

Interventions

experimental group:ICU treatment and external diaphragmatic pacing
Control group:ICU treatment

Sponsors

Jiangsu Province Hospital ( First Affiliated Hospital of Nanjing Medical University )
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. above 18 years old 2. receiving mechanical ventilation treatment 3. after 48 hours of mechanical ventilation,the respiratory support parameters were relatively stable 4. the patient 's vital signs were stable 5. no neck,chest and abdomen treatment contraindications 6. did not participate in other clinical trials 7. The patient 's guardian signed the informed consent

Exclusion criteria

Exclusion criteria: 1. Pregnancy status 2. There were serious injuries in the neck, chest and abdomen, which affected the activity of the diaphragm 3. severe chest ( abdominal ) cavity effusion or gas accumulation 4. history of malignant tumor and peripheral neuromuscular disease

Design outcomes

Primary

MeasureTime frame
diaphragm thickness;diaphragm mobility;Ventilator weaning rate;

Secondary

MeasureTime frame
The duration of mechanical ventilation;mortality;The rate of secondary mechanical ventilation;Length of ICU stay;Total length of hospital stay;hospitalization expenses;Activity of Daily Living,ADL;

Countries

China

Contacts

Public ContactZheng Yu

Jiangsu Province Hospital ( First Affiliated Hospital of Nanjing Medical University )

pdj2009@yeah.net+86 158 6218 3011

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026