Residual neuromuscular blockade
Conditions
Interventions
Gold Standard:After general anesthesia, the neuromuscular monitor is used to assess the TOF ratio (TOFR) of the hand's adductor pollicis muscle. When TOFR is greater than or equal to 0.9, it indicates
Index test:Preoperatively and postoperatively, patients' grip strength is measured using a dynamometer, and the timing of extubation is determined by combining the TOF ratio from the neuromuscular mon
Sponsors
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University,
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria were as follows: (1) Individuals aged =18 years and <80 years; (2) Inclusion criteria: ? 18 years old = age < 80 years old. ? Elective surgical patients. ? Able to cooperate independently and communicate without barriers. ? The anesthesia method is intravenous inhalation combined anesthesia. ? Voluntarily participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria include patients with the following conditions: (1) preoperative spinal cord injury, cerebral infarction or hemorrhage; (2) autoimmune disease-related muscle disorders, such as myasthenia gravis, amyotrophic lateral sclerosis, and multiple sclerosis; (3) preoperative hypoxemia; (4) severe hearing or communication disorders; (5) inability or impossibility to assess muscle strength in both upper limbs; (6) tracheotomy; (7) difficult airways as defined by anesthesiologists; (8) pending pathological results. Exclusion criteria eliminated during the study period: (1) unexpected transfer to the ICU due to changes in the patient's condition; (2) immediate extubation after admission to PACU; (3) emergency intervention required due to intraoperative bleeding or anaphylactic shock; (4) postoperative delirium affecting cooperation. These criteria are designed to maintain consistency and controllability of the environment when assessing the impact of hand dynamometers on tracheal intubation extubation for patients undergoing elective general anesthesia surgery in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Handgrip Strength Recovery Cutoff Value; | — |
Secondary
| Measure | Time frame |
|---|---|
| Richmond Agitation-Sedation Scale (RASS) Score;Diagnostic Performance of the Handgrip Strength Recovery Cutoff Value Model; | — |
Countries
China
Contacts
Public ContactLV KAI
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University,
Outcome results
None listed