Gastroscopy for children
Conditions
Interventions
Propofol group (Group P):Intravenous injection of fentanyl (1µg/kg) + propofol (2mg/kg)
Remazolam group (Group R):Intravenous injection of fentanyl (1µg/kg) + remazolam (0.2mg/kg)
Sponsors
The Second Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
6 Years to 14 Years
Inclusion criteria
Inclusion criteria: (1) Pediatric gastroenterologists evaluate children requiring gastroscopy; (2) Aged 6 to 14 years old; (3) BMI 18-28kg/m2; (4) ASA grade I-II.
Exclusion criteria
Exclusion criteria: (1) Children (family members) who refuse to participate in the observation, do not cooperate, and cannot communicate; (2) Acute respiratory inflammation within 2 weeks and no cure; (3) Have a history of serious heart, brain, lung and metabolic diseases; (4) People with serious blood system diseases; (5) People with neuromuscular system diseases or mental diseases; (6) Abnormal liver and kidney function; (7) Evaluate children with difficult airway (Mallampati score level III or above) or those requiring tracheal intubation; (8) Those allergic to remazolam and propofol; (9) Participate in other drug clinical trials 3 months before inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation success rate;Mean arterial pressure;Pulse oxygen saturation;Heart rate;Respiratory rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of sedation onset;bispectral index;Time of recovery;Operating room exit time; | — |
Countries
China
Contacts
Public ContactXie Kun
The Second Hospital of Shandong University
Outcome results
None listed