Chronic atrophic gastritis with intestinal metaplasia
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria of chronic atrophic gastritis with intestinal metaplasia; (2) Prior to enrollment, electronic gastroscopy and histopathology confirmed atrophy (reduced intrinsic glands) with mild or moderate enterosis (intestinal metaplasia), with or without mild or moderate dysplasia; (2) Consistent with the TCM diagnosis and syndrome differentiation of chronic atrophic gastritis with intestinal metaplasia; (3) Gender is not limited, age between 18 and 75 years old; (4) The patient's informed consent and willingness to accept the appropriate treatment; (5) Voluntary signing of informed consent.
Exclusion criteria
Exclusion criteria: (1) autoimmune gastritis; (2) Patients with other serious complications such as malignant tumors; (3) Gastric mucosa with high-grade intraepithelial neoplasia or suspected malignant transformation by pathological diagnosis; (4) Those who are taking aspirin, warfarin and other anticoagulants, or have coagulation disorders; (5) Patients with serious primary diseases such as heart, brain, liver, kidney, lung and blood system; (6) Women who are lactating or even pregnant; (7) Complicated with serious mental illness, unclear description of their own symptoms, unable to cooperate; (8) Patients who are participating in clinical trials of other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| gastroscope ;pathological examination;Immunohistochemical detection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Chronic atrophic gastritis PRO scale score ;TCM syndrome accumulation table ; | — |
Countries
China
Contacts
Wangjing Hospital, China Academy of Chinese Medical Sciences