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The effects of enteral nutrition with different energy densities on muscle mass, gastrointestinal function, and microbiota in critically ill patients

The effects of enteral nutrition with different energy densities on muscle mass, gastrointestinal function, and microbiota in critically ill patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085199
Enrollment
Unknown
Registered
2024-06-03
Start date
2024-06-10
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critically ill patients

Interventions

High energy density group:Interventional high-energy density enteral nutrition
Standard energy density group:Interventional low-energy density enteral nutrition

Sponsors

Central People's Hospital of Zhanjiang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1: The clinical situation is relatively stable: a. Blood flow is stable; b. Lactic acid<6mmol/L; c. No or only small doses of vasoactive drugs are needed 2: Clinical treatment drugs do not affect gastrointestinal function 3: Informed consent of family members and their patients

Exclusion criteria

Exclusion criteria: 1: Patients with uncontrolled shock, severe hypoxemia and acidosis, active upper gastrointestinal bleeding, intestinal ischemia, intestinal obstruction, high flow intestinal fistula, abdominal compartment syndrome, etc 2: Vulnerable groups: such as women, children, the elderly, other special groups such as detainees, etc 3: Family members and their patients are unwilling to cooperate with the examination

Design outcomes

Primary

MeasureTime frame
Gastric residue;Gastric motility;Intestinal diameter, fold thickness, and peristalsis;Intestinal flora;

Secondary

MeasureTime frame
Sebum thickness (triceps, subscapular angle, and abdominal wall);Muscle circumference (upper arm circumference, thigh circumference, and calf circumference);

Countries

China

Contacts

Public ContactXinmei Li

Central People's Hospital of Zhanjiang

15040970@qq.com+86 135 4206 2375

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026