Postoperative delirium
Conditions
Interventions
Non-sleep disorders group:None
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: Preoperative diagnosis of hip/knee arthritis In the spinal canal anesthesia elective hip/knee arthroplasty =65 years old ASA grade: I-III
Exclusion criteria
Exclusion criteria: Patients with a prior history of psychiatric disorders such as delirium, Parkinson's disease, and Alzheimer's disease Patients with a history of previous intracranial surgery, cerebral hemorrhage, or cerebral infarction Patients who are judged by the investigator to be unable to communicate due to speech or hearing problems Refused to sign a consent form
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative delirium assessed by CAM (Confusion Assessment Method);PSQI (Pitts burgh sleep quality index);objective sleep quality and sleep structure;Saccades and event-related potentials;fMRI (Functional Magnetic Resonance Imagine); | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative delirium severity assessed by MDAS (Memorial Delirium Assessment Scale);AIS (Athens Insomnia Scale) score;ISI (Insomnia Severity Indeex) score;Indicators of peripheral blood;ADL (Activity of Daily Living) score;Assessment of pain;MMSE (Mini-mental State Examination);MoCA (Montreal Cognitive Assessment);Frail score;CCI (Charlson Comorbidity Index);HAMA-14 (Hamilton Anxiety Scale-14);HAMD-17 (Hamilton Depression Scale-17);Indicators of cerebrospinal fluid;Indicators of saliva; | — |
Countries
China
Contacts
Public ContactHan Yongzheng
Peking University Health Science Center, 38 Xueyuan Road, Haidian
Outcome results
None listed