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Effect and mechanism of upper limb rehabilitation training controlled by multimodal brain computer interface on brain plasticity in chronic stroke

Effect and mechanism of upper limb rehabilitation training controlled by multimodal brain computer interface on brain plasticity in chronic stroke

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085173
Enrollment
Unknown
Registered
2024-05-31
Start date
2024-06-01
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

MI+SSVEP-BCI intervention group:MI+SSVEP-BCI
MI-BCI intervention group:MI-BCI
SSVEP-BCI intervention group:SSVEP-BCI

Sponsors

Yangpu Hospital, School of Medicine, Tongji University, Shanghai, China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? First-ever episode of stroke; ? The stroke lesion is unilateral; ? Diagnosed as subcortical ischemic stroke by computed tomography (CT) or magnetic resonance imaging (MRI); ? Age between 30-80 years old; ? Disease duration of 3-24 months; ? Hemiplegia exists, with the Brunnstrom stage of the affected hand = Stage V; ? Mini-mental state examination (MMSE) score = 20; ? Able to sit independently in a chair for at least 1 hour and cooperate with assessment and treatment; ? The patient or their authorized representative has signed the informed consent form.

Exclusion criteria

Exclusion criteria: ? Severe impairment of cognitive function or inability to pay attention to and understand screen information; ? Allergy to EEG electrode paste; ? Implanted devices such as cardiac pacemaker, intracranial pacemaker, deep brain stimulation, etc.; ? Pregnancy; ? Severe spasms or pain; ? Bone and joint diseases (including joint deformities) that may lead to spasms in the hand or upper limb joints, other severe neurological diseases, liver and kidney function impairment, etc.; ? Unstable fractures in the hemiplegic upper limb.

Design outcomes

Primary

MeasureTime frame
FM-UL;ARAT;MSS;

Secondary

MeasureTime frame
FIM;ERD/ERS;MI accuracy;

Countries

China

Contacts

Public ContactJiali Li

Yangpu Hospital, School of Medicine, Tongji University

15618939902@163.com+86 156 1893 9902

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026