Neurosurgery
Conditions
Interventions
Ciprofol group (group C) :In the ciprofol group, sufentanil was injected intravenously for 10s, and ciprofol was injected 0.4mg/kg for 30s after 2 minutes.
Propofol group (group P):In propofol group, sufentanil was injected intravenously for 10s, and propofol 2.0mg/kg for 30s was injected 2min later
Sponsors
Department of Anesthesiology,the Affiliated Brain Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. American College of Anesthesiologists (ASA) Grade I - III 2. Ages 18-65 3. 18.5< BMI <30
Exclusion criteria
Exclusion criteria: 1. Pregnant or menstruating 2. Severe circulatory and respiratory diseases combined with hemodynamic instability 3. Severe liver dysfunction (aspartate transaminase/alanine transaminase =2.5) and severe renal dysfunction (serum creatinine =2mg/dl) 4. Patients with poorly controlled hypertension [systolic blood pressure =160 mmHg and/or diastolic blood pressure =100 mmHg] 5. People who are expected to have difficult airways 6. Patients with diseased sinus syndrome and allergies to the investigatory drugs or drugs that may be used in the course of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of general anesthesia induction;Success rate of inhibition of the intubation reflex; | — |
Secondary
| Measure | Time frame |
|---|---|
| MOAA/S ;Narcotrend index; | — |
Countries
China
Contacts
Public ContactLu Fangzhou
The Affiliated Brain Hospital of Nanjing Medical University
Outcome results
None listed