postpartum hemorrhage
Conditions
Interventions
experimental group:Tranexamic acid 0.6g
control group:Tranexamic acid 1.0g
Sponsors
Nanjing Drum Tower Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: • Gestation =28 weeks • Pregnant woman > 18 years old • Vaginal delivery • Bleeding =500ml or overt bleeding 0.9) • Understanding and signing informed consent
Exclusion criteria
Exclusion criteria: • History of seizures or seizures • History of venous or arterial thrombosis, including deep vein thrombosis, pulmonary embolism, heartache, myocardial infarction, stroke; Hereditary thrombotic predisposition or presence of diseases predisposed to thromboembolic events: thromboembolism, antiphospholipid antibody syndrome, systemic lupus erythematosus. • Renal insufficiency • Acquired color vision deficiency • Subarachnoid hemorrhage • Active intravascular coagulation • Allergy to tranatemic acid or any component • Inability to sign consent forms, cognitive or intellectual disability
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total postpartum bleeding in 24 hours;Incidence of severe postpartum hemorrhage(=1000ml/24h); | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood transfusion rate within 48 hours postpartum (red cell suspension); | — |
Countries
China
Contacts
Public ContactDai Yimin
Nanjing Drum Tower Hospital,
Outcome results
None listed