Breast cancer
Conditions
Interventions
Index test:A multimodal-based prediction model for non-sentinel lymph node metastasis
Sponsors
Yunnan Cancer Hospital (The Third Affiliated Hospital of Kunming Medical University)
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients with primary breast cancer 2. Positive sentinel lymph node biopsy and axillary lymph node dissection. 3. No neoadjuvant chemotherapy, radiotherapy or ablation prior to surgery. 4. MRI within 3 weeks prior to surgery.
Exclusion criteria
Exclusion criteria: 1. recurrent breast cancer or history of surgery or radiation therapy in the axilla 2. Inflammatory breast cancer 3. Bilateral breast cancer or metastatic breast cancer 4. previous or current history of other malignant tumors 5. Sentinel lymph node count > 5 6. missing frozen H&E stained sections of sentinel lymph nodes 7. Mass ROI too small (voxel less than 64) or MRI unclear 8. Incomplete clinicopathologic data
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whole slide image of sentinel lymph node (H&E);Non-sentinel lymph node metastatic status;Accuracy, Sensitivity, Specificity;Area under the curve;Positive predictive value, Negative predictive value; | — |
Countries
China
Contacts
Public ContactGuojun Zhang
Yunnan Cancer Hospital (The Third Affiliated Hospital of Kunming Medical University)
Outcome results
None listed