obese
Conditions
Interventions
experimental group:Intravenous infusion of dexmedetomidine 1ug/kg(LBW)
control group:Pump an equal amount of physiological saline at the same time
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ? Body mass index (BMI) = 30kg/m2; ? ASA II-III level; ? Age range from 18 to 65 years old.
Exclusion criteria
Exclusion criteria: ? Severe cardiovascular and pulmonary diseases; ? Abnormal liver and kidney function; ? Individuals who are allergic to general anesthesia or dexmedetomidine; ? Individuals with atrioventricular block; ? Patients with difficult airways; ? Preoperative use of analgesics, sedatives, or drugs that affect hemodynamics; ? Pregnant or lactating women; ? Individuals with neurological and psychiatric disorders; ? Individuals with poor control of hypertension; ? Refuse to join the experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DBP;SBP;MAP;HR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Set value of sufentanil effect site concentration;Postoperative pain;Dexmedetomidine dosage during the test;sufentanil dosage during the test; propofol dosage during the test;rocuronium dosage during the test;infusion volume during the test; | — |
Countries
China
Contacts
Public ContactFaPing Tu
Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed