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A multicenter clinical RCT research on mechanism of frailty in the elderly and effect of intelligent rehabilitation technologies involving virtual reality and whole body vibration vs resistance training basing on multi-omics analysis

Mechanism and effects of modern rehabilitation technologies (virtual reality and whole body vibration) vs conventional rehabilitation in the elderly with frailty basing on bioinformation analysis: A Multicenter, Randomized, Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085102
Enrollment
Unknown
Registered
2024-05-30
Start date
2024-06-01
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

frailty in the elderly

Interventions

virtual reality training group:virtual reality training
whole-body vibration Group:whole-body vibration training Whole-body vibration training will last 12 weeks. Participants will be required to stand on the moveable rectangular platform and positioned th
resistance training group:The resistance training mainly includes pedaling training with regular dosage and time of treatments for 12 weeks.

Sponsors

Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
70 Years to 100 Years

Inclusion criteria

Inclusion criteria: Eligible subjects were identified as old patients (men and women aged 70 years or over) with frailty. The inclusion criteria were: older adults aged 70 years or over, meeting 3 or more of the Fried Frailty Criteria, and understanding and consenting to participate this study. All eligible subjects will receive the verbal and written information and gIve their written consent to participate in this study.

Exclusion criteria

Exclusion criteria: Exclusion criteria were serious diseases likely to be associated with a life expectancy of less than 12 months; or severe cognitive impairment (defined as having a Mini Mental State Examination score of 18 or less); or contraindications for whole-body vibration and virtual reality training such as recent fractures (=6 months), gallbladder or kidney stones, malignancies, rheumatic arthritis, epilepsy, serious heart sicknesses or an implant, and bypass stent or cardiac pacemaker. And people who did not meet all of the inclusion criteria or who did not consent to participate would not be included.

Design outcomes

Primary

MeasureTime frame
Body weight;Frailty status;timed up and go test(TUGT);6 meters walking test (6mWT);Short Physical Performance Battery (SPPB);handgrip strength;Maximal isometric knee extensor (quadriceps) strength;—

Secondary

MeasureTime frame
Bone Mineral Density (BMD);—

Countries

China

Contacts

Public ContactZhang Li

Chinese PLA General Hospital

zhangli781230@163.com+86 186 0122 4462

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026