Skip to content

A novel submucosa steroid injection strategy to prevent esophageal stricture following whole circumferential endoscopic submucosal dissection of superficial cancer of the esophagus

A novel submucosa steroid injection strategy to prevent esophageal stricture following whole circumferential endoscopic submucosal dissection of superficial cancer of the esophagus

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085095
Enrollment
Unknown
Registered
2024-05-30
Start date
2023-05-23
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophagus cancer

Interventions

Experimental group:Submucosal steroid injection

Sponsors

Lanzhou University Second Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who histologically confirmed superficial esophagus cancer expected to result in a mucosal defect involving the entire esophageal circumference after ESD ; 2. Signed informed consent;

Exclusion criteria

Exclusion criteria: 1. Lymph node metastases detected by computed tomography; 2. Receiving additional adjuvant treatments, such as chemotherapy; 3. Submucosal invasion exceeding 200 micrometers (>SM1) in pretreatment endoscopic findings; 4. Poorly controlled diabetes mellitus; 5. Ongoing use of corticosteroids; 6. Organ failure; 7. Concurrence of another active cancer; 8. Coagulation disorders; 9. Inability to tolerate intravenous anesthesia.

Design outcomes

Primary

MeasureTime frame
The incidence of esophageal stricture after ESD;

Secondary

MeasureTime frame
The number of sessions of endoscopic balloon dilation (EBD);The rate of adverse events;

Countries

China

Contacts

Public ContactPengfei Wang

Lanzhou University Second Hospital

wpfw@foxmail.com+86 181 5367 3602

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026