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The monitoring of intraoperative nociceptive stimulation in pediatric patients: A clinical study on the impact of post tonsillectomy and adenoidectomy pain management

The monitoring of intraoperative nociceptive stimulation in pediatric patients: A clinical study on the impact of post tonsillectomy and adenoidectomy pain management

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085061
Enrollment
Unknown
Registered
2024-05-30
Start date
2024-06-01
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain of post tonsil and adenoid surgery in pediatric

Interventions

Group N (Group NOX):Connection NOX monitor, maintain NOX index between 30 to 50, when NOX above 50 or below 30, increase or decrease, fentanyl infusion rate 0.05 mu g/kg/min each time, adjusted to mai
Group S (Group SPI):The SPI monitor was connected to maintain the SPI index between 20 and 50. When the SPI was higher than 50 or lower than 20, the remifentanil infusion rate was increased or decreas
Group R (Group R):According to the change of the child's heart rate, the effect-site concentration of remifentanil was adjusted to ensure that the heart rate fluctuated between 80% and 120% of the bas

Sponsors

Foshan Maternity & Child Healthcare Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. 3-12 years old kids, ASA?~?,BMI=15.5kg/m² BMI=24.5kg/m² 2. Tonsil and adenoid surgery under general anesthesia

Exclusion criteria

Exclusion criteria: 1. Co-existed with with arrhythmia (sinus bradycardia), mental and psychological diseases and chronic pain diseases 2. Allergic to anesthesia and its related components used in surgery 3. Anesthetics, sedatives, antiemetics and antipruritic agents were used 72h before surgery 4. Preoperative acute upper respiratory tract infection, asthma history, temperature more than 38 ° C 5. Severe sleep apnea syndrome 6. The guardians of the children were informed and refused to participate in the study

Design outcomes

Primary

MeasureTime frame
Total opioid consumption;Incidence of agitation during recovery;Time from surgery completion to extubation time;Time of PACU staying ;

Secondary

MeasureTime frame
Postoperative pain scale (FLACC);Postoperative emergency delirum score (PAED);Total consumption of propofol;Time of extubation aftersurgery;Postoperative adverse reaction in 24 hours after surgery;Parent satisfaction;Staff satisfaction;

Countries

China

Contacts

Public ContactYe Yuping

Foshan Maternity & Child Healthcare Hospital

pcia.yy@163.com+86 757 8296 9979

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026