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The efficacy and safety of low opioid multimodal analgesia and traditional opioid analgesia in cesarean section: a randomized controlled trial

The efficacy and safety of low opioid multimodal analgesia and traditional opioid analgesia in cesarean section: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085055
Enrollment
Unknown
Registered
2024-05-30
Start date
2024-06-01
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effectiveness and safety of low opioid multimodal analgesia and traditional opioid analgesia in cesarean section

Interventions

Multi mode analgesia with low opioid regimen (Group E) and conventional analgesia management group (Group C).:postoperative analgesia with combination of low opioid and bilateral transverse abdominis
conventional intravenous analgesia:Postoperative analgesia with sufentany intravenous infusion

Sponsors

Maternal and Child Health Hospital of Hubei Province
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: ? Age = 18 years old, American Society of Anesthesiologists anesthesia classification II-III; ? All are cephalic, full-term, single birth mothers; ? Meets the indications for cesarean section; ? All are transverse incisions of the lower segment of the uterus

Exclusion criteria

Exclusion criteria: ? Accompanied by severe pregnancy complications; ? High risk factors such as congenital malformations, placental abruption, and placenta previa; ? Breast developmental defects; ? Abnormal fetal position and head pelvic imbalance; ? Concomitant mental illness; ? Severe dysfunction of important organs; ? Recent use of analgesics or dependence on analgesics; ? There are contraindications to anesthesia drugs.

Design outcomes

Primary

MeasureTime frame
Postoperative pain assessment;Postoperative recovery assessment;Opioid dosage within 48 hours postoperatively;Remedial analgesic conditions;Occurrence of adverse reactions;Neonatal outcomes;Breastfeeding situation;Neonatal neurobehavioral score;

Secondary

MeasureTime frame
Long term outcome;

Countries

China

Contacts

Public ContactShen Chan

Maternal and Child Health Hospital of Hubei Province

sunnyabs1215@163.com+86 189 8616 1976

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026