neonatal necrotizing enterocolitis
Conditions
Interventions
Exposure group (Positive exposure factors for pregnancy-related exposures, exposures during neonatal hospitalization, and biospecimen markers.):None
Non-exposed group (Negative exposure factors for pregnancy-related exposures, exposures during neonatal hospitalization, and biospecimen markers.):None
Sponsors
Longgang District Maternity & Child Healthcare Hospital of Shenzhen City
Eligibility
Sex/Gender
All
Age
No minimum to 0.5 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria comprise necrotizing enterocolitis that meets Stage 2 or higher ("confirmed necrotizing enterocolitis") according to the Bell staging criteria, with informed consent obtained from the guardian.
Exclusion criteria
Exclusion criteria: Food protein-induced enterocolitis syndrome will be excluded. Individuals with fewer than one follow-up examination will also be excluded. Congenital gastrointestinal malformations, such as spontaneous intestinal perforation and congenital hypertrophic pyloric stenosis, will likewise be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| severe necrotizing enterocolitis;Physical growth indicators in children with necrotizing enterocolitis at the day of discharge and corrected 18-24 months of age;Neurodevelopmental impairment in children with necrotizing enterocolitis at corrected 18-24 months of age; | — |
Secondary
| Measure | Time frame |
|---|---|
| Health care needs of children with necrotizing enterocolitis between hospital discharge and corrected 18-24 months of age; | — |
Countries
China
Contacts
Public ContactXin Guo
Longgang District Maternity & Child Healthcare Hospital of Shenzhen City
Outcome results
None listed