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Correlation analysis between postoperative pain index and intestinal barrier function impairment in patients undergoing gastrointestinal laparoscopic surgery

Correlation analysis between postoperative pain index and intestinal barrier function impairment in patients undergoing gastrointestinal laparoscopic surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400085037
Enrollment
Unknown
Registered
2024-05-30
Start date
2024-06-01
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pain

Interventions

observation group:None

Sponsors

Changzhi People's Hospital affiliated with Changzhi Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Patients who underwent gastrointestinal laparoscopic surgical treatment under general anesthesia in our hospital from June 2024 to September 2024, male and female, aged 50-70 years, ASA classification I-III. 2.Cardio and pulmonary function not abnormal 3.Liver and kidney function not abnormal 4.Good patient compliance and cooperation to complete the required tests 5.Patients and their families sign an informed consent form 6.Patient is not participating in other clinical trials

Exclusion criteria

Exclusion criteria: 1. History of abdominal surgery 2. Pre-operative radiotherapy treatment 3. Presence of autoimmune diseases 4. Combined hematologic diseases

Design outcomes

Primary

MeasureTime frame
D-lactic acid;intestinal fatty acid binding protein;diamine oxidase;ratio of actulose to mannitol;LPS;

Secondary

MeasureTime frame
Height and weight;complication;Surgical time, bleeding volume, urine volume, and dosage of opioid drugs used;Nausea and vomiting;

Countries

China

Contacts

Public ContactWu Jie; Zhang Jialei

Changzhi People's Hospital affiliated with Changzhi Medical College

zjlbigeye@163.com+86 155 2517 6091

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026