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Construction of a Risk Prediction Model for Bone Marrow Inhibition after Chemotherapy for Gastric Cancer Based on the Combination of Inflammatory Composite Indicators and PNI

Construction of a Risk Prediction Model for Bone Marrow Inhibition after Chemotherapy for Gastric Cancer Based on the Combination of Inflammatory Composite Indicators and PNI

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400085036
Enrollment
Unknown
Registered
2024-05-30
Start date
2024-06-01
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone marrow suppression after chemotherapy for gastric cancer

Interventions

Sponsors

Changde First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) The diagnosis of gastric cancer meets the diagnostic criteria of the 2022 NCCN guidelines; (2) The XELOX regimen has been evaluated as effective in anti-tumor therapy; (3) Age range from 18 to 75 years old; (4) KPS scoring function status score = 70 points; (5) The laboratory examination results and clinical pathological data before chemotherapy are complete, and the follow-up data after chemotherapy are complete.

Exclusion criteria

Exclusion criteria: (1) Merge primary tumors from other locations; (2) Merge bone marrow and blood related diseases; (3) Severe heart, lung, liver, and kidney diseases, etc; (4) Patients receiving prophylactic use of colony stimulating factor drugs before chemotherapy; (5) The patient did not sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
systemic immune-inflammation index,SII;neutrophilto lymphocyte ratio,NLR;plateletto lymphocyte ratio,PLR;prognostic nutritional index,PNI;

Countries

China

Contacts

Public ContactKexia CHEN

Changde First People's Hospital

597139143@qq.com+86 135 7516 8136

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026