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The effect and mechanism of M2 synovial macrophages in rheumatoid arthritis

The effect and mechanism of M2 synovial macrophages in rheumatoid arthritis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400085034
Enrollment
Unknown
Registered
2024-05-30
Start date
2024-05-30
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid arthritis

Interventions

Sponsors

Tianjin Medical University General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) The diagnosis aligns with the RA classification criteria established by the American College of Rheumatology (ACR) in 2010 and the European League Against Rheumatism (EULAR). 2) Patients aged over 18 and under 80 years, of any gender. 3) Patients participate in the study voluntarily, exhibit good compliance, and possess the capability to comprehend and sign the informed consent form before the study. 4) During surgery, samples of synovial tissue from the inflamed joint area can be collected.

Exclusion criteria

Exclusion criteria: 1) Concurrent presence of other rheumatic diseases; 2) Coexistence of malignant tumors; 3) Currently experiencing acute or chronic infections, or having a history of active tuberculosis; 4) History of immunodeficiency, acquired or congenital immunodeficiency disorders, or organ transplants; 5) Presence of psychiatric disorders or other obstacles to compliance.

Design outcomes

Primary

MeasureTime frame
M1 macrophages;M2 macrophages;

Countries

China

Contacts

Public ContactXin Li

Tianjin Medical University General Hospital

limbourg@163.com+86 133 0212 3520

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026