stroke
Conditions
Interventions
Control group:rTMS pseudostimulation + conventional rehabilitation
Stimulation Group 1 (Primary motor cortex,M1):rTMS acts on M1+ conventional rehabilitation
Stimulation Group 2(Supplementary Motor Area, SMA):rTMS acts on SMA+ conventional rehabilitation
Sponsors
The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) The diagnosis meets the diagnostic criteria for cerebrovascular disease formulated by the Chinese Medical Association in 2010 and is confirmed by CT or MRI examination; (2) Patients with stable vital signs, first onset, and disease course within 2 years; (3) Mental clarity, upper limb muscle strength = grade 3, muscle tone = grade 1+, Brunnstrom = grade 3; (4) Assessed by MMSE scale with greater than or equal to 20 points, cognitive ability cooperation test; (5) Sitting balance level 2 or above; (6) Patients who have been informed about the experiment and agree to participate in the experiment after publicity and mobilization; (7) Visual acuity/normal visual acuity after correction, and assessment and training can be completed
Exclusion criteria
Exclusion criteria: (1) Patients with cognitive impairment and mental disorders; (2) Patients with contraindications to transcranial magnetic (electrodes made of silver or gold in the skull, metal brain implants; The distance between the electronic components in the body and the TMS coil is less than 10cm; personal history of epilepsy or other factors that may lower the seizure threshold); (3) Patients with severe comorbidities such as heart, liver, kidney, and brain failure; (4) Patients who have undergone or systematically rehabilitated before.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serial reaction time task,SRTT;ADL assessment:MB;Assessment of upper limb function:Fugl-Meyer; | — |
Secondary
| Measure | Time frame |
|---|---|
| Muscle tone rating :M Ashworth;Quality of life evaluation:SF-12;Emotional situation(HAMA,HAMD);Functional near-infrared spectroscopy (fNIRS) acquisition; motor evoked potentials; | — |
Countries
China
Contacts
Public ContactGuangxu Xu
The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital)
Outcome results
None listed