Heart failure
Conditions
Interventions
control group:Western medicine
experimental group:Western medicine combined with Chinese medicine
Sponsors
Liyang Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Voluntary participation and informed consent; (2) Age 18-90 years old, gender unlimited; (3) A history of chronic heart failure for more than 3 months or clinical findings of heart failure symptoms for more than 3 months; (4) NYHA cardiac function grade ?-?; (5) EF < 50% measured by Simpson method; (6) At least 2 weeks of standardized drug therapy; (7) TCM syndrome is consistent with Qi deficiency and blood stasis;
Exclusion criteria
Exclusion criteria: (1) does not meet the inclusion criteria; (2) Heart failure caused by non-cardiogenic causes, congenital heart disease, acute heart failure, or heart failure after acute myocardial infarction; (3) Patients who plan to undergo coronary revascularization therapy and cardiac resynchronization therapy within 8 weeks; (4) unrepaired valvular heart disease with myocarditis, aneurysm, left ventricular outflow tract obstruction, and significant hemodynamic changes; (5) Patients with severe primary diseases of liver and kidney and serious abnormal liver and kidney function; (6) Cancer patients, psychiatric patients, patients with serious diseases of the blood, nervous system, endocrine system; (7) Patients with cardiogenic shock, uncontrolled malignant arrhythmias, sinus or atrioventricular block of grade II type II or above without pacemaker therapy, progressive aggravation of unstable angina pectoris or acute myocardial infarction; (8) Patients with uncontrolled hypertension with systolic blood pressure of 180/mmHg and/or diastolic blood pressure of 110mmHg; Systolic blood pressure < 90mmHg and/or diastolic blood pressure < 60mmHg; (9) Patients participating in clinical trials of other drugs; (10) Pregnant or preparing to become pregnant and lactating women; (11) People who are allergic, or have been known to be allergic to therapeutic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NT-proBNP;Left Ventricular Ejection Fraction;Minnesota Quality of Life Scale Rating;Hamilton Depression Scale;Changes in Traditional Chinese Medicine Syndrome Points and Therapeutic Effects; | — |
Secondary
| Measure | Time frame |
|---|---|
| TNF-a;interleukin 6;6-minute walking test ;5-HT;CRP; | — |
Countries
China
Contacts
Public ContactChunhui Huang
Liyang Hospital of Traditional Chinese Medicine
Outcome results
None listed