Pain After Cesarean Section
Conditions
Interventions
Group B:A bilateral, 2-point classic TAP block with 0.2% bupivacaine hydrochloride(20 mL each side
40 mL total for each)
Group LB:A bilateral, 2-point classic TAP block with LB 266 mg
Dilute 20ml (266mg) of bupivacaine liposomes with 20ml of physiological saline to a total volume of 40ml, 20ml per side
Sponsors
Guangzhou Medical University Affiliated Women and Children's Medical Center
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Women who were scheduled to undergo elective cesarean delivery under spinal anesthesia 2. term gestation (37-42 weeks), 3. American Society of Anesthesiologists physical status of II or III 4. Aged 18 to 45 years; 5. Patients voluntarily participate in the trial and sign an informed consent form 6. Healthy single pregnancy
Exclusion criteria
Exclusion criteria: 1.BMI =40kg/m^2 2.Contraindications to spinal anesthesia 3.Participant received antipsychotic or hypnotic medications, alcohol or drug abuse; 4.Severe pregnancy complications (gestational diabetes, gestational hypertension, heart disease, complete placenta previa, placental abruption, preeclampsia); 5.Allergy, intolerance or contraindication to drugs used in the study; 6.Known fetal abnormalities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 48h PCA Dosage of opioid drugs in PCA pump within 48 hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| Motor blockade;Side effects;Uterine contraction pain;Wound pain at rest (VAS-R) after cesarean section;Provocative wound while changing position in bed (VAS-P) after cesarean sectionafter cesarean section;First time to use PCA;Time to oral acetaminophen ;Time to out-of-bed activity;Time to first exhaust;Satisfaction with analgesia; | — |
Countries
China
Contacts
Public ContactChen Xi
Guangzhou Medical University Affiliated Women and Children's Medical Cente
Outcome results
None listed