sensitive skin syndrom
Conditions
Interventions
Group A:Topical cream
Group B:Topical cream + LED Yellow light
Group C:Topical cream + LED Red-Yellow light
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for sensitive skin: (1) Subjective symptoms: Manifested as skin irritation by physical, chemical, mental and other factors, it is easy to burn, sting, itch and tightness; (2) Exclude primary diseases that may be accompanied by sensitive skin, such as: rosacea, seborrheic dermatitis, hormone-dependent dermatitis, contact dermatitis, atopic dermatitis and swollen lupus erythematosus; (2) Agree to conduct objective evaluation of the test (including lactate stinging test, capsaicin test and measurement of objective parameters); (3) Signed informed consent;
Exclusion criteria
Exclusion criteria: (1) Those who have oral contraceptives within half a year, pregnant or lactating women; (2) Patients with severe cardiovascular system diseases, severe liver and kidney insufficiency, elderly patients with a history of severe diabetes, and those with a history of mental illness; (3) Those who cannot avoid sun exposure due to long-term outdoor work; (4) Exclude primary diseases that may be accompanied by sensitive skin, such as: rosacea, seborrheic dermatitis, hormone-dependent dermatitis, contact dermatitis, atopic dermatitis and swollen lupus erythematosus; (5) Patients who have received oral medication (such as anti-inflammatory, antihistamines) and photoelectric therapy (such as intense pulsed light, radiofrequency) within two weeks before being included in the study; (6) Patients judged by the clinical trial investigator to be unsuitable for this trial; (7) Patients with a history of allergy to visible light or a positive photosensitivity test; (8) Patients who have recently participated in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SS-10 score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Erythema index, EI;transepidermal water loss, TEWL;pH;sebum content; | — |
Countries
China
Contacts
Public ContactChengfeng Zhang
Huashan Hospital, Fudan University
Outcome results
None listed