Obesity
Conditions
Interventions
The sequential propofol and remifentanil group (PR group):During intravenous general anesthesia, propofol was administered first followed by remifentanil.
The sequential remifentanil and propofol group (PR group):During intravenous general anesthesia, remifentanil was administered first followed by propofol.
Sponsors
The First Affiliated Hospital of Jinan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1: Patients requiring preoperative painless gastroscopy for bariatric surgery, no gender limit, no age limit. 2: Body mass index (BMI) > 30 kg/m2. 3: ASA grade: I-III. 4: Patients and their families agreed and signed the informed consent for anesthesia.
Exclusion criteria
Exclusion criteria: 1: Patients with central nervous system disorders, psychiatric disorders, or verbal communication disorders. 2: Patients with a history of abnormal surgical anesthesia recovery. 3: Patients allergic to propofol, remifentanil and other anesthetic drugs. 4: Alcohol dependence. 5: Patients who were lactating or had long-term use of opioids or non-steroidal drugs before surgery. 6: Long-term use of ß-blockers and heart rate <50 beats/min. 7: Severe heart, brain, liver, kidney, respiratory dysfunction or dysfunction. 8: Subjects were uncooperative, unavailable for follow-up, or judged by the investigator to be likely to have difficulty completing the study. 9: Other conditions that were judged by the investigator to be ineligible.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hypoxemia;Incidence and duration of severe hypoxemia;Maximum and minimum heart rates;The lowest pulse oxygen saturation ;Coughing/body movement;The satisfaction of the three parties (patients, endoscopists and anesthesiologists) on the effect of anesthesia;The Brice questionnaire;The type of anesthesia to be selected for the next gastroscopy; | — |
Countries
China
Contacts
Public ContactMengxia Wang
The First Affiliated Hospital of Jinan University
Outcome results
None listed