Osteoarthritis
Conditions
Interventions
Experimental group:Normal receive routine OA therapy medications such as glucosamine, celecoxib, etc. The affected limb was subjected to ischemic conditioning using the armbands for sphygmomanometer o
Control group:Only conventional OA medications such as glucosamine and celecoxib are accepted.
Sponsors
China-Japan Union Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
55 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Subjects were between 55 and 80 years old (including 55 and 80 years old), and gender was not limited; (2) Osteoarthritis Kellgren-Lawrence grading standard grade I-III; (3) Stable vital signs and normal liver and kidney functions; (4) Body mass index 18 = BMI = 35; (5) Clinical diagnosis to undergo total knee arthroplasty; (6) Have not participated in other clinical trials within 3 months; (7) Subjects are fully aware of the benefits and risks of this trial and are still willing to participate and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Have broken skin, vesicular swelling, soft tissue damage, and vascular damage to the lower extremities; (2) Suffering from bleeding disorders; (3) Combined with serious primary diseases such as cardiovascular, cerebrovascular, hepatic, renal and hematopoietic systems; (4) Patients with abnormal mental behavior who cannot cooperate; (5) Those who have recently taken special drugs, such as antiepileptic drugs and immunosuppressants; (6) Blood pressure >200/110 mm Hg or <90/60 mm Hg; (7) Others whom the investigators considered unsuitable for enrollment, such as those who could not undergo efficacy determination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC score; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score;HSS score, OARSI score;Beck Anxiety Inventory, Beck Depression Inventory; | — |
Countries
China
Contacts
Public ContactZuo Jianlin
China-Japan Union Hospital of Jilin University
Outcome results
None listed