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The Efficacy and Safety of Propofol Single or Combined Sedation in Patients After Oral and Maxillofacial Surgery: A Retrospective Clinical Trial

The Efficacy and Safety of Propofol Single or Combined Sedation in Patients After Oral and Maxillofacial Surgery: A Retrospective Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400084983
Enrollment
Unknown
Registered
2024-05-29
Start date
2023-03-01
Completion date
Unknown
Last updated
2024-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral and maxillofacial

Interventions

propofol+midazolam group:NA
propofol+dexmedetomidine group:NA

Sponsors

Nanfang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1: patients who were admitted to the Department of Critical Care Medicine of Nanfang Hospital of Southern Medical University from September 2017 to February 2022 2: Age = 18 years old 3: Patients who had received sedation and analgesia treatment during the stay in ICU 4: Patients who had received invasive mechanical ventilation treatment during the stay in ICU.

Exclusion criteria

Exclusion criteria: 1: admitted to ICU because of other reasons, such as sepsis/septic shock, cardiac arrest, etc 2: Severe liver and kidney dysfunction (such as liver function grade up to Child-Pugh 3, or renal function has reached uremic stage). 3: Those who cannot obtain monitoring data

Design outcomes

Primary

MeasureTime frame
Delirium incidence;

Secondary

MeasureTime frame
Sedation success rate;Extubation time;Duration of mechanical ventilation;Length of ICU stay;Length of hospital;Safety events;Risk factors for delirium;

Countries

China

Contacts

Public ContactZhenhua Zeng

Nanfang Hospital, Southern Medical University

zhenhuazeng.2008@163.com+86 156 9242 8912

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026