inherited thrombophilia
Conditions
Interventions
hereditary thrombophilia group:Not applicable
Sponsors
Fujian Maternity and Child Health Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: (1) Antithrombin deficiency (<60%) (2) Protein C deficiency (<65%) (3) Protein S deficiency (<55%) (4) Prothrombin F2 deficiency (5) FV mutation (6) Gestational age less than 7 weeks (7)No anticoagulant medication used
Exclusion criteria
Exclusion criteria: 1: Women with anatomical genital anomalies clearly diagnosed by ultrasound or hysterosalpingography 2: Couples or embryos with chromosomal abnormalities 3: Women with a history of taking teratogenic drugs early in pregnancy 4: Systemic or localized immune abnormalities of the reproductive tract (e.g., antiphospholipid syndrome) 5: Ongoing use of anticoagulants such as heparin analogs, warfarin, direct oral anticoagulants, etc. 6. Over 35 years of age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| venous thromboembolism; | — |
Secondary
| Measure | Time frame |
|---|---|
| abortion;prematurity;Smaller than gestational age;pre-eclampsia;eclampsia;HELLP syndrome;abruption of the placenta;stillbirth; | — |
Countries
China
Contacts
Public ContactZhang Jinhua
Fujian Maternity and Child Health Hospita
Outcome results
None listed