obesity
Conditions
Interventions
Case series:NA
Sponsors
Renji Hospital, Shanghai Jiao Tong University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: i. Meet the diagnostic criteria for obesity (BMI=28kg/m2); Adult male waist =90cm, adult female waist =85cm, or waist-to-hip ratio > 1.0; ii. Ages 18-65; iii. Have not previously received any drug therapy or weight loss surgery affecting glucose and lipid metabolism; iv. Consent to venous blood collection and MRI examination without any contraindications related to examination;
Exclusion criteria
Exclusion criteria: i. have been diagnosed with secondary obesity, such as hypothyroidism, Cushing's syndrome, polycystic ovary syndrome, etc.; ii. Severe cardiovascular and cerebrovascular diseases, rheumatism and immunity diseases; iii. Severe metabolic diseases, such as diabetic ketoacidosis, hyperosmolar hyperglycemia, etc. iv. Advanced malignant tumors; v. Pregnancy and lactation; A known history of drug use that affects glycolipid metabolism, such as glucocorticoids, antibiotics, anti-anxiety or antidepressants; vii. Severe bleeding tendency and inability to complete venous blood collection; viii. There are MRI contraindications, such as patients with cardiac pacemakers, nerve stimulators, artificial metal heart valves, etc.; Pregnant patients; Claustrophobic; Epilepsy patients, etc. ix. Patients who refuse to undergo or are unable to cooperate with an MRI examination; x. Other conditions that the researcher deems inappropriate to study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CMR;MRI of both lower limbs;Abdominal MRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Related indicators of glucose and lipid metabolism; | — |
Countries
China
Contacts
Public ContactJing Ma
Renji Hospital, Shanghai Jiao Tong University
Outcome results
None listed