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Cancelled by the investigator.The effect of high PEEP method versus intermittent subglottic suction method to clear the subglottic secretions on artificial airway endotracheal tube cuff in mechanically ventilated patients with ARDS: A randomized controlled study

The effect of high PEEP method to clear the stagnant phlem on artificial airway bag in mechanically ventilated patients with ARDS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400084973
Enrollment
Unknown
Registered
2024-05-29
Start date
2024-06-01
Completion date
Unknown
Last updated
2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute respiratory distress syndrome

Interventions

High PEEP group:High PEEP method
intermittent subglottic suction group:Sterilize the subglottic suction catheter's aperture and set the suction device's negative pressure to between 100 and 150 mmHg. Then attach the suction catheter

Sponsors

Shandong Provincial Hospital Affiliated to Shandong First Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ? patients aged >18 years who met the medical diagnosis of ARDS based on the Berlin definition; ? ventilation mode was mechanical ventilation and the retained artificial airway was available for subglottic suction.

Exclusion criteria

Exclusion criteria: ? patients with undrained pneumothorax; ? patients with interstitial pneumonia; ? patients with extremely unstable hemodynamics, such as systolic blood pressure lower than 90 mmHg; ? those who have already had VAP and have not yet recovered when admitted to the ICU.

Design outcomes

Primary

MeasureTime frame
The presence of subglottic secretions;

Secondary

MeasureTime frame
Choking and man-machine confrontation incidence;microsorption incidence;ventilator-associated pneumonia;Changes in SPO2;Duration of mechanical ventilation;Length of ICU hospitalization;

Countries

China

Contacts

Public ContactLiufang Pang

Shandong Provincial Hospital Affiliated to Shandong First Medical University

m15169095281@163.com+86 158 6529 2161

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026