Effect of inhaled oxygen concentration on lung function
Conditions
Interventions
Group A:Use of 30% inhaled oxygen concentration
Group B:Use of 50% inhaled oxygen concentration
Group C:Use of 80% inhaled oxygen concentration
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1)Age greater than 65 and less than 90 years old; (2)ASA classification I-III; (3)Elective laparoscopic surgery patients, the operation requires a pneumoperitoneum time of not less than 90 minutes; (4)BMI<28 kg/m2; (5) Patients with normal preoperative electrocardiogram, arterial oxygenation, and partial pressure of carbon dioxide; (6) Signed informed consent form
Exclusion criteria
Exclusion criteria: (1) emergency surgery, unplanned reoperation; (2) contraindication of arterial catheterization; (3) Severe heart, lung, liver and renal insufficiency; (4) Preoperative complicated with obvious respiratory diseases, such as COPD, severe;respiratory infection, pulmonary infection, etc; (5) Preoperative SpO2 = 90% or PaO2 = 60mmHg when breathing air, preoperative hemoglobin < 90g / L; (6) it is expected that there is a difficult airway;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AaDO2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygenation index;Partial pressure of arterial blood carbon dioxide;VD/VT;PaO2;heart rate;Hb;Postoperative nausea and vomiting;Ppeak;Pplat;blood pressure; | — |
Countries
China
Contacts
Public ContactWang Bin
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed