Early onset Parkinson's disease
Conditions
Interventions
verum acupuncture group:basic pharmacotherapy+verum acupuncture
sham acupuncture group:basic pharmacotherapy+sham acupuncture
wait-list group:basic pharmacotherapy
Sponsors
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
25 Years to 49 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for Parkinson's disease; 2. Age 25-49 years; 3. Hoehn-Yahr stage 1-4; 4. Clear consciousness, stable vital signs, and able to communicate normally; 5. Willing to sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Parkinson's syndrome caused by various causes such as cerebrovascular disease, poisoning, progressive supranuclear palsy, multiple system atrophy, lewy body dementia and corticobasal ganglia degeneration; (2) Those with more serious diseases, such as serious liver and kidney, blood, tumors, endocrine diseases or pain; (3) Participants in clinical trials of other drugs and acupuncture at the same time; (4) mental patients; (5) People who are deaf or have communication disabilities; (6) A history of alcoholism or drug abuse; (7) Women who are pregnant or planning to become pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Unified Parkinson's Disease Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Parkinson's disease non-motor Symptom Assessment Scale;Parkinson’s Disease Daily Quality of Life-39 ;Synapsys human posture balance system;3D gait analysis;Musculoskeletal ultrasound;Resting-state functional magnetic resonance imaging;Diffusion tensor imaging;Proton magnetic resonance spectroscopy; | — |
Countries
China
Contacts
Public ContactNanbu Wang
State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed