Anesthetic cough
Conditions
Interventions
EK group:Esketamine 0.2mg/kg is injected within 1 min before sufentanil injection
C group:3ml normal saline was infused intravenously 1 minute before the sufentanil injection
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Individuals aged 18-70 years, with ASA grades I-II, and preparing for elective general anesthesia tracheal intubation.
Exclusion criteria
Exclusion criteria: Refusal of participants, ASA grades>II, BMI = 30kg/m2, severe liver and kidney dysfunction, history of chronic cough, history of bronchial asthma, chronic obstructive pulmonary disease, acute upper respiratory tract infection, recent use of bronchodilators and steroid hormones, angiotensin-converting enzyme inhibitors, psychiatric patients, hypertension, patients with allergic reactions to study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of cough;The severity of cough; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs;MMSE;Postoperative anesthesia recovery time;Satisfaction with anesthesia;Directional force recovery time;NRS;Agitation score; | — |
Countries
China
Contacts
Public ContactYan Peng
The First Affiliated Hospital of Soochow University
Outcome results
None listed