cervical carcinoma and Ovarian Carcinoma
Conditions
Interventions
Treatment group:Administer bevacizumab for treatment
Sponsors
Jiangnan University Affiliated Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Visit from January 1, 2023 to December 31, 2023 2) Age = 18 years old 3) Cervical or ovarian cancer patients verified by histology or cytology 4) Indications for the use of bevacizumab based on clinical diagnostic criteria 5) ECOG score 0-1 points 6) The subjects received a treatment regimen containing bevacizumab in combination with chemotherapy, radiation therapy, etc
Exclusion criteria
Exclusion criteria: 1) Patients with concomitant malignant tumors 2) Individuals who are allergic to bevacizumab and its excipients 3) Severe injuries to the liver, kidneys, hematopoiesis, and cardiovascular system 4) Pregnant or lactating women 5) Patients with previous gastrointestinal perforation and fistula, including gallbladder perforation, who have undergone major surgery four weeks before medication, or whose wounds have not healed four weeks before medication 6) Patients with tumor infiltration into large blood vessels or proximal tracheal and bronchial networks, or recent occurrence of pulmonary hemorrhage/hemoptysis (>1/2 teaspoon of fresh red blood), or other risks of major bleeding; 7) Researchers believe that other conditions that are not suitable for treatment, such as active tuberculosis, cardiovascular accidents, cerebrovascular accidents, drug use, alcoholism, and other bad habits
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression free survival;Objective relief rate;Describe the number and proportion of users of bevacizumab combined with chemotherapy/radiotherapy/PARP inhibitors in cervical and ovarian cancer subjects, respectively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reaction incidence rate;Types and severity of adverse reactions; | — |
Countries
China
Contacts
Public ContactJinjin YU
Jiangnan University Affiliated Hospital
Outcome results
None listed